SVHC
Candidate List of Substances of Very High Concern for authorization
Updated 253 / 4-FEB-2026
This list is the European Union’s Directive 1907/2006 (REACH) of SVHC’s (Substances of
Very High Concern). There are 253 substances total, organized in sections of the month and year
that they were official placed on the candidate list. Inclusion on this list does not necessarily mean
that these substances are banned in the EU but have been included for future study and action.
Click here to see the ECHA website and follow up on these substances.
รายชื่อ Candidate List of Substances of Very High Concern for authorization 253 มีดังนี้
| Substance Name | EC Number | CAS Number | Date of inclusion | Reason for inclusion | Decision number | |
| 1 | n-hexane | 203-777-6 | 110-54-3 | 4/2/2026 | Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
D(2025)7771-DC |
| 2 | 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol and its salts | - | - | 4/2/2026 | Toxic for reproduction (Article 57c) | D(2025)7771-DC |
| 3 | 1,1'-(ethane-1,2-diyl)bis[pentabromobenzene](DBDPE) | 284-366-9 | 84852-53-9 | 5/11/2025 | Very persistent and very bioaccumulative, vPvB (Article 57e) | D(2025)6375-DC |
| 4 | 1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane | 241-867-7 | 17928-28-8 | 25/6/2025 | Very persistent and very bioaccumulative, vPvB (Article 57e) | D(2025)4165-DC |
| 5 | Decamethyltetrasiloxane | 205-491-7 | 141-62-8 | 25/6/2025 | Very persistent and very bioaccumulative, vPvB (Article 57e) | D(2025)4165-DC |
| 6 | Tetra(sodium/potassium) 7-[(E)-{2-acetamido-4-[(E)-(4-{[4-chloro-6-({2-[(4-fluoro-6-{[4-(vinylsulfonyl)phenyl]amino}-1,3,5-triazine-2-yl)amino]propyl}amino)-1,3,5-triazine-2-yl]amino}-5-sulfonato-1-naphthyl)diazenyl]-5-methoxyphenyl}diazenyl]-1,3,6-naphthalenetrisulfonate; Reactive Brown 51 | 466-490-7 | - | 25/6/2025 | Toxic for reproduction (Article 57c) | D(2025)4165-DC |
| 7 | 6-[(C10-C13)-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid | 701-118-1 | 2156592-54-8 | 21/1/2025 | Toxic for reproduction (Article 57c) | D(2024)7663-DC |
| 8 | O,O,O-triphenyl phosphorothioate | 209-909-9 | 597-82-0 | 21/1/2025 | Persistent, bioaccumulative and toxic, PBT(Article 57d) | D(2024)7663-DC |
| 9 | Octamethyltrisiloxane | 203-497-4 | 107-51-7 | 21/1/2025 | Very persistent, very bioaccumulative, vPvB(Article 57e) | D(2024)7663-DC |
| 10 | Perfluamine | 206-420-2 | 338-83-0 | 21/1/2025 | Very persistent, very bioaccumulative, vPvB(Article 57e) | D(2024)7663-DC |
| 11 | Reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives | 421-820-9 | 192268-65-8 | 21/1/2025 | Persistent, bioaccumulative and toxic, PBT(Article 57d) | D(2024)7663-DC |
| 12 | Triphenyl Phosphate | 204-112-2 | 115-86-6 | 7/11/2024 | Endocrine disrupting properties (Article 57(f) - environment) | D(2024)6225-DC |
| 13 | Bis(α,α-dimethylbenzyl) peroxide | 201-279-3 | 80-43-3 | 2024/6/27 | Toxic for reproduction (Article 57c) | D(2024)4144-DC |
| 14 | 2,4,6-tri-tert-butylphenol | 211-989-5 | 732-26-3 | 2024/1/23 | Toxic for reproduction (Article 57c) Persistent, bioaccumulative and toxic (PBT) (Article 57d) |
D(2023)8585-DC |
| 15 | 2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol | 221-573-5 | 3147-75-9 | 2024/1/23 | Very persistent and very bioaccumulative (vPvB) (Article 57e) |
D(2023)8585-DC |
| 16 | 2-(dimethylamino)-2-[(4-methylphenyl)methyl]-1-[4-(morpholin-4-yl)phenyl]butan-1-one | 438-340-0 | 119344-86-4 | 2024/1/23 | Toxic for reproduction (Article 57c) | D(2023)8585-DC |
| 17 | Bumetrizole | 223-445-4 | 3896-11-5 | 2024/1/23 | vPvB (Article 57e) | D(2023)8585-DC |
| 18 | Oligomerisation and alkylation reaction products of 2-phenylpropene and phenol | 700-960-7 | - | 2024/1/23 | vPvB (Article 57e) | D(2023)8585-DC |
| 19 | Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide | 278-355-8 | 75980-60-8 | 2023/6/14 | Toxic for reproduction (Article 57c) | D(2023)3788-DC |
| 20 | Bis(4-chlorophenyl) sulphone | 201-247-9 | 80-07-9 | 2023/6/14 | vPvB (Article 57e) | D(2023)3788-DC |
| 21 | reaction mass of 2,2,3,3,5,5,6,6-octafluoro-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)morpholine and 2,2,3,3,5,5,6,6-octafluoro-4-(heptafluoropropyl)morpholine | 473-390-7 | - | 2023/1/17 | vPvB (Article 57e) | D(2022)9120-DC |
| 22 | Perfluoroheptanoic acid and its salts | - | - | 2023/1/17 | Toxic for reproduction (Article 57c)#PBT (Article 57d)#vPvB (Article 57e)#Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)#Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) | D(2022)9120-DC |
| 23 | Melamine | 203-615-4 | 108-78-1 | 2023/1/17 | Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)#Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) | D(2022)9120-DC |
| 24 | Isobutyl 4-hydroxybenzoate | 224-208-8 | 4247-02-3 | 2023/1/17 | Endocrine disrupting properties (Article 57(f) - human health) | D(2022)9120-DC |
| 25 | bis(2-ethylhexyl) tetrabromophthalate covering any of the individual isomers and/or combinations thereof | - | - | 2023/1/17 | vPvB (Article 57e) | D(2022)9120-DC |
| 26 | Barium diboron tetraoxide | 237-222-4 | 13701-59-2 | 2023/1/17 | Toxic for reproduction (Article 57c) | D(2022)9120-DC |
| 27 | 4,4'-sulphonyldiphenol | 201-250-5 | 80-09-1 | 2023/1/17 | Toxic for reproduction (Article 57c)#Endocrine disrupting properties (Article 57(f) - environment)#Endocrine disrupting properties (Article 57(f) - human health) | D(2022)9120-DC |
| 28 | 2,2',6,6'-tetrabromo-4,4'-isopropylidenediphenol | 201-236-9 | 79-94-7 | 2023/1/17 | Carcinogenic (Article 57a) | D(2022)9120-DC |
| 29 | 1,1'-[ethane-1,2-diylbisoxy]bis[2,4,6-tribromobenzene] | 253-692-3 | 37853-59-1 | 2023/1/17 | vPvB (Article 57e) | D(2022)9120-DC |
| 30 | N-(hydroxymethyl)acrylamide | 213-103-2 | 924-42-5 | 2022/6/10 | Carcinogenic (Article 57a) Mutagenic (Article 57b) |
D(2022)4187-DC |
| 31 | tris(2-methoxyethoxy)vinylsilane | 213-934-0 | 1067-53-4 | 2022/1/17 | Toxic for reproduction (Article 57c) | D(2021)10043-DC |
| 32 | S-(tricyclo(5.2.1.0'2,6)deca-3-en-8(or 9)-yl O-(isopropyl or isobutyl or 2-ethylhexyl) O-(isopropyl or isobutyl or 2-ethylhexyl) phosphorodithioate | 401-850-9 | 255881-94-8 | 2022/1/17 | PBT (Article 57d) | D(2021)10043-DC |
| 33 | 6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol | 204-327-1 | 119-47-1 | 2022/1/17 | Toxic for reproduction (Article 57c) | D(2021)10043-DC |
| 34 | (±)-1,7,7-trimethyl-3-[(4-methylphenyl)methylene]bicyclo[2.2.1]heptan-2-one covering any of the individual isomers and/or combinations thereof (4-MBC) | - | - | 2022/1/17 | Endocrine disrupting properties (Article 57(f) - human health) | D(2021)10043-DC |
| 35 | Phenol, alkylation products (mainly in para position) with C12-rich branched alkyl chains from oligomerisation, covering any individual isomers and/ or combinations thereof (PDDP) | - | - | 2021/7/8 | Toxic for reproduction (Article 57c) | D(2021)4569-DC |
| 36 | orthoboric acid, sodium salt | - | - | 2021/7/8 | Toxic for reproduction (Article 57c) | D(2021)4569-DC |
| 37 | Medium-chain chlorinated paraffins (MCCP) | - | - | 2021/7/8 | PBT (Article 57d) | D(2021)4569-DC |
| 38 | glutaral | 203-856-5 | 111-30-8 | 2021/7/8 | Respiratory sensitising properties (Article 57(f) - human health) | D(2021)4569-DC |
| 39 | 4,4'-(1-methylpropylidene)bisphenol | 201-025-1 | 77-40-7 | 2021/7/8 | Endocrine disrupting properties (Article 57(f) - environment) Endocrine disrupting properties (Article 57(f) - human health) |
D(2021)4569-DC |
| 40 | 2-(4-tert-butylbenzyl)propionaldehyde and its individual stereoisomers | - | - | 2021/7/8 | Toxic for reproduction (Article 57c) | D(2021)4569-DC |
| 41 | 2,2-bis(bromomethyl)propane-1,3-diol (BMP); 2,2-dimethylpropan-1-ol, tribromo derivative/3-bromo-2,2-bis(bromomethyl)-1-propanol (TBNPA); 2,3-dibromo-1-propanol (2,3-DBPA) | - | - | 2021/7/8 | Carcinogenic (Article 57a) | D(2021)4569-DC |
| 42 | 1,4-dioxane | 204-661-8 | 123-91-1 | 2021/7/8 | Carcinogenic (Article 57a) Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
D(2021)4569-DC |
| 43 | Bis(2-(2-methoxyethoxy)ethyl)ether | 205-594-7 | 143-24-8 | 2021/1/19 | Toxic for reproduction (Article 57c) | D(2020)9139-DC |
| 44 | Dioctyltin dilaurate, stannane, dioctyl-, bis(coco acyloxy) derivs., and any other stannane, dioctyl-, bis(fatty acyloxy) derivs. wherein C12 is the predominant carbon number of the fatty acyloxy moiety | - | - | 2021/1/19 | Toxic for reproduction (Article 57c) | D(2020)9139-DC |
| 45 | Dibutylbis(pentane-2,4-dionato-O,O')tin | 245-152-0 | 22673-19-4 | 2020/6/25 | Toxic for reproduction (Article 57c) | D(2020)4578-DC |
| 46 | butyl 4-hydroxybenzoate | 202-318-7 | 94-26-8 | 2020/6/25 | Endocrine disrupting properties (Article 57(f) - human health) | D(2020)4578-DC |
| 47 | 2-methylimidazole | 211-765-7 | 693-98-1 | 2020/6/25 | Toxic for reproduction (Article 57c) | D(2020)4578-DC |
| 48 | 1-vinylimidazole | 214-012-0 | 1072-63-5 | 2020/6/25 | Toxic for reproduction (Article 57c) | D(2020)4578-DC |
| 49 | Perfluorobutane sulfonic acid (PFBS) and its salts | - | - | 2020/1/16 | Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
ECHA/01/2020 |
| 50 | Diisohexyl phthalate | 276-090-2 | 71850-09-4 | 2020/1/16 | Toxic for reproduction (Article 57c) | ECHA/01/2020 |
| 51 | 2-methyl-1-(4-methylthiophenyl)-2-morpholinopropan-1-one | 400-600-6 | 71868-10-5 | 2020/1/16 | Toxic for reproduction (Article 57c) | ECHA/01/2020 |
| 52 | 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone | 404-360-3 | 119313-12-1 | 2020/1/16 | Toxic for reproduction (Article 57c) | ECHA/01/2020 |
| 53 | 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid, its salts and its acyl halides (covering any of their individual isomers and combinations thereof) |
- | - | 2019/7/16 | Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
ED/71/2019 |
| 54 | 2-methoxyethyl acetate | 203-772-9 | 110-49-6 | 2019/7/16 | Toxic for reproduction (Article 57c) | ED/71/2019 |
| 55 | 4-tert-butylphenol | 202-679-0 | 98-54-4 | 2019/7/16 | Endocrine disrupting properties (Article 57(f) - environment) | ED/71/2019 EU/2019/1194 |
| 56 | Tris(4-nonylphenyl, branched and linear) phosphite (TNPP) | - | - | 2019/7/16 | Endocrine disrupting properties (Article 57(f) - environment) | D(2024)7663-DC ED/71/2019 |
| 57 | 1,7,7-trimethyl-3-(phenylmethylene)bicyclo[2.2.1]heptan-2-one | 239-139-9 | 15087-24-8 | 2019/1/15 | Endocrine disrupting properties (Article 57(f) - environment) | ED/88/2018 EU/2018/2013 |
| 58 | 2,2-bis(4'-hydroxyphenyl)-4-methylpentane | 401-720-1 | 6807-17-6 | 2019/1/15 | Toxic for reproduction (Article 57c) | ED/88/2018 |
| 59 | Benzo[k]fluoranthene | 205-916-6 | 207-08-9 | 2019/1/15 | Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e) |
ED/88/2018 |
| 60 | Fluoranthene | 205-912-4 | 206-44-0 93951-69-0 |
2019/1/15 | PBT (Article 57d) vPvB (Article 57e) |
ED/88/2018 |
| 61 | Phenanthrene | 201-581-5 | 85-01-8 | 2019/1/15 | vPvB (Article 57e) | ED/88/2018 |
| 62 | Pyrene | 204-927-3 | 129-00-0 1718-52-1 |
2019/1/15 | PBT (Article 57d) vPvB (Article 57e) |
ED/88/2018 |
| 63 | Benzene-1,2,4-tricarboxylic acid 1,2 anhydride ; trimellitic anhydride; TMA | 209-008-0 | 552-30-7 | 2018/6/27 | Respiratory sensitising properties (Article 57(f) - human health) | ED/61/2018 EU/2018/594 |
| 64 | Benzo[ghi]perylene | 205-883-8 | 191-24-2 | 2018/6/27 | PBT (Article 57d) vPvB (Article 57e) |
ED 61/2018 |
| 65 | Decamethylcyclopentasiloxane | 208-764-9 | 541-02-6 | 2018/6/27 | PBT (Article 57d) vPvB (Article 57e) |
ED 61/2018 |
| 66 | Dicyclohexyl phthalate ; DCHP | 201-545-9 | 84-61-7 | 2018/6/27 | Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - human health) |
EU/2018/636 ED/61/2018 |
| 67 | Disodium octaborate | 234-541-0 | 12008-41-2 | 2018/6/27 | Toxic for reproduction (Article 57c) | ED 61/2018 |
| 68 | Dodecamethylcyclohexasiloxane | 208-762-8 | 540-97-6 | 2018/6/27 | PBT (Article 57d) vPvB (Article 57e) |
ED 61/2018 |
| 69 | Ethylenediamine ; EDA | 203-468-6 | 107-15-3 | 2018/6/27 | Respiratory sensitising properties (Article 57(f) - human health) | ED 61/2018 |
| 70 | Lead | 231-100-4 | 7439-92-1 | 2018/6/27 | Toxic for reproduction (Article 57c) | ED 61/2018 |
| 71 | Octamethylcyclotetrasiloxane | 209-136-7 | 556-67-2 | 2018/6/27 | PBT (Article 57d) vPvB (Article 57e) |
ED 61/2018 |
| 72 | Terphenyl, hydrogenated | 262-967-7 | 61788-32-7 | 2018/6/27 | vPvB (Article 57e) | ED 61/2018 |
| 73 | Benz[a]anthracene | 200-280-6 | 56-55-3 1718-53-2 |
2018/1/15 | Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e) |
ED 01/2018 |
| 74 | Cadmium carbonate | 208-168-9 | 513-78-0 | 2018/1/15 | Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
ED 01/2018 |
| 75 | Cadmium hydroxide | 244-168-5 | 21041-95-2 | 2018/1/15 | Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
ED 01/2018 |
| 76 | Cadmium nitrate | 233-710-6 | 10022-68-1 10325-94-7 |
2018/1/15 | Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
ED 01/2018 |
| 77 | Chrysene | 205-923-4 | 218-01-9 1719-03-5 |
2018/1/15 | Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e) |
ED 01/2018 |
| 78 | 1,6,7,8,9,14,15,16,17,17,18,18- Dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene (“Dechlorane Plus”™) [covering any of its individual anti- and syn-isomers or any combination thereof] | - | - | 2018/1/15 | vPvB (Article 57e) | ED 01/2018 |
| 79 | Reaction products of 1,3,4-thiadiazolidine-2,5-dithione, formaldehyde and 4-heptylphenol, branched and linear (RP-HP) [with ≥0.1% w/w 4-heptylphenol, branched and linear (4-HPbl)] | - | - | 2018/1/15 | Endocrine disrupting properties (Article 57(f) - environment) | ED 01/2018 |
| 80 | Perfluorohexane-1-sulphonic acid and its salts | - | - | 2017/7/7 | vPvB (Article 57e) | ED/30/2017 |
| 81 | 4,4’-isopropylidenediphenol (bisphenol A; BPA) | 201-245-8 | 80-05-7 | 2017/1/12 | Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - human health) Endocrine disrupting properties (Article 57(f) - environment) |
ED/01/2017 ED/30/2017 |
| 82 | Nonadecafluorodecanoic acid (PFDA) and its sodium and ammonium salts | 206-400-3 - 221-470-5 |
335-76-2 3830-45-3 3108-42-7 |
2017/1/12 | Toxic for reproduction (Article 57c) PBT (Article 57d) |
ED/01/2017 |
| 83 | p-(1,1-dimethylpropyl)phenol | 201-280-9 | 80-46-6 | 2017/1/12 | Equivalent level of concern having probable serious effects to environment (Article 57f) | ED/01/2017 |
| 84 | 4-heptylphenol, branched and linear [substances with a linear and/or branched alkyl chain with a carbon number of 7 covalently bound predominantly in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof] |
- | - | 2017/1/12 | Equivalent level of concern having probable serious effects to environment (Article 57f) | ED/01/2017 |
| 85 | Benzo[def]chrysene ; Benzo[a]pyrene | 200-028-5 | 50-32-8 | 2016/6/20 | Carcinogenic (Article 57a)#Mutagenic (Article 57b)#Toxic for reproduction (Article 57c)#PBT (Article 57 d)#vPvB (Article 57 e) | ED/21/2016 |
| 86 | 1,3-propanesultone | 214-317-9 | 1120-71-4 | 2015/12/17 | Carcinogenic (Article 57 a) | ED/79/2015 |
| 87 | 2,4-di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol (UV-327) | 223-383-8 | 3864-99-1 | 2015/12/17 | vPvB (Article 57 e) | ED/79/2015 |
| 88 | 2-(2H-benzotriazol-2-yl)-4-(tert-butyl)-6-(sec-butyl)phenol (UV-350) | 253-037-1 | 36437-37-3 | 2015/12/17 | vPvB (Article 57 e) | ED/79/2015 |
| 89 | Nitrobenzene | 202-716-0 | 98-95-3 | 2015/12/17 | Toxic for reproduction (Article 57 c) | ED/79/2015 |
| 90 | Perfluorononan-1-oic-acid and its sodium and ammonium salts | 206-801-3 | 375-95-1 21049-39-8 4149-60-4 |
2015/12/17 | Toxic for reproduction (Article 57 c) PBT (Article 57 d) |
ED/79/2015 |
| 91 | 1,2-benzenedicarboxylic acid, di-C6-10-alkyl esters; 1,2-benzenedicarboxylic acid, mixed decyl and hexyl and octyl diesters with ≥ 0.3% of dihexyl phthalate (EC No. 201-559-5) | 271-094-0; 272-013-1 | 68515-51-5; 68648-93-1 | 2015/6/15 | Toxic for reproduction (Article 57 c) | ED/39/2015 |
| 92 | 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [1], 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [2] [covering any of the individual stereoisomers of [1] and [2] or any combination thereof] | 2015/6/15 | vPvB (Article 57e) | ED/39/2015 | ||
| 93 | 2-(2H-benzotriazol-2-yl)-4,6-ditertpentylphenol (UV-328) | 247-384-8 | 25973-55-1 | 2014/12/17 | PBT (Article 57 d); vPvB (Article 57 e) | ED/108/2014 |
| 94 | 2-benzotriazol-2-yl-4,6-di-tert-butylphenol (UV-320) | 223-346-6 | 3846-71-7 | 2014/12/17 | PBT (Article 57 d); vPvB (Article 57 e) | ED/108/2014 |
| 95 | reaction mass of 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate and 2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (reaction mass of DOTE and MOTE) | - | - | 2014/12/17 | Toxic for reproduction (Article 57 c) | ED/108/2014 |
| 96 | Cadmium fluoride | 232-222-0 | 7790-79-6 | 2014/12/17 | Carcinogenic (Article 57 a); Mutagenic (Article 57 b); Toxic for reproduction (Article 57 c); Equivalent level of concern having probable serious effects to human health (Article 57 f) | ED/108/2014 |
| 97 | Cadmium sulphate | 233-331-6 | 10124-36-4,31119-53-6 | 2014/12/17 | Carcinogenic (Article 57 a); Mutagenic (Article 57 b); Toxic for reproduction (Article 57 c); Equivalent level of concern having probable serious effects to human health (Article 57 f) | ED/108/2014 |
| 98 | 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (DOTE) | 239-622-4 | 15571-58-1 | 2014/12/17 | Toxic for reproduction (Article 57 c) | ED/108/2014 |
| 99 | Cadmium chloride | 233-296-7 | 10108-64-2 | 2014/6/16 | Carcinogenic (Article 57a); Mutagenic (Article 57b); Toxic for reproduction (Article 57c); Equivalent level of concern having probable serious effects to human health (Article 57 f) | ED/49/2014 |
| 100 | 1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear | 271-093-5 | 68515-50-4 | 2014/6/16 | Toxic for reproduction (Article 57 c) | ED/49/2014 |
| 101 | Sodium peroxometaborate | 231-556-4 | 7632-04-4 | 2014/6/16 | Toxic for reproduction (Article 57 c) | ED/49/2014 |
| 102 | Sodium perborate; perboric acid, sodium salt | 239-172-9; 234-390-0 | - | 2014/6/16 | Toxic for reproduction (Article 57 c) | ED/49/2014 |
| 103 | Cadmium sulphide | 215-147-8 | 1306-23-6 | 2013/12/16 | Carcinogenic (Article 57a); Equivalent level of concern having probable serious effects to human health (Article 57 f) | ED/121/2013 |
| 104 | Disodium 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis(4-aminonaphthalene-1-sulphonate) (C.I. Direct Red 28) | 209-358-4 | 573-58-0 | 2013/12/16 | Carcinogenic (Article 57a); | ED/121/2013 |
| 105 | Disodium 4-amino-3-[[4'-[(2,4-diaminophenyl)azo][1,1'-biphenyl]-4-yl]azo] -5-hydroxy-6-(phenylazo)naphthalene-2,7-disulphonate (C.I. Direct Black 38) | 217-710-3 | 1937-37-7 | 2013/12/16 | Carcinogenic (Article 57a); | ED/121/2013 |
| 106 | Dihexyl phthalate | 201-559-5 | 84-75-3 | 2013/12/16 | Toxic for reproduction (Article 57 c); | ED/121/2013 |
| 107 | Imidazolidine-2-thione; (2-imidazoline-2-thiol) | 202-506-9 | 96-45-7 | 2013/12/16 | Toxic for reproduction (Article 57 c); | ED/121/2013 |
| 108 | Lead di(acetate) | 206-104-4 | 301-04-2 | 2013/12/16 | Toxic for reproduction (Article 57 c); | ED/121/2013 |
| 109 | Trixylyl phosphate | 246-677-8 | 25155-23-1 | 2013/12/16 | Toxic for reproduction (Article 57 c); | ED/121/2013 |
| 110 | Cadmium | 231-152-8 | 7440-43-9 | 20/6/2013 | Carcinogenic (Article 57a); Equivalent level of concern having probable serious effects to human health (Article 57 f) | ED/69/2013 |
| 111 | Ammonium pentadecafluorooctanoate (APFO) | 223-320-4 | 3825-26-1 | 2013/6/20 | Toxic for reproduction (Article 57 c); PBT (Article 57 d) | ED/69/2013 |
| 112 | Pentadecafluorooctanoic acid (PFOA) | 206-397-9 | 335-67-1 | 2013/6/20 | Toxic for reproduction (Article 57 c); PBT (Article 57 d) | ED/69/2013 |
| 113 | Dipentyl phthalate (DPP) | 205-017-9 | 131-18-0 | 2013/6/20 | Toxic for reproduction (Article 57 c); | ED/69/2013 |
| 114 | 4-Nonylphenol, branched and linear, ethoxylated [substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, ethoxylated covering UVCB- and well-defined substances, polymers and homologues, which include any of the individual isomers and/or combinations thereof] | 2013/6/20 | Equivalent level of concern having probable serious effects to the environment (Article 57 f) | ED/69/2013 | ||
| 115 | Cadmium oxide | 215-146-2 | 1306-19-0 | 2013/6/20 | Carcinogenic (Article 57a); Equivalent level of concern having probable serious effects to human health (Article 57 f) | ED/69/2013 |
| 116 | Hexahydromethylphthalic anhydride [1], Hexahydro-4-methylphthalic anhydride [2], Hexahydro-1-methylphthalic anhydride [3], Hexahydro-3-methylphthalic anhydride [4] [The individual isomers [2], [3] and [4] (including their cis- and trans- stereo isomeric forms) and all possible combinations of the isomers [1] are covered by this entry] | 247-094-1, 243-072-0, 256-356-4, 260-566-1 | 25550-51-0, 19438-60-9, 48122-14-1, 57110-29-9 | 2012/12/19 | Equivalent level of concern having probable serious effects to human health (Article 57 f) | ED/169/2012 |
| 117 | 6-methoxy-m-toluidine (p-cresidine) | 204-419-1 | 120-71-8 | 2012/12/19 | Carcinogenic (Article 57a) | ED/169/2012 |
| 118 | Cyclohexane-1,2-dicarboxylic anhydride [1], cis-cyclohexane-1,2-dicarboxylic anhydride [2], trans-cyclohexane-1,2-dicarboxylic anhydride [3] [The individual cis- [2] and trans- [3] isomer substances and all possible combinations of the cis- and trans-isomers [1] are covered by this entry] | 201-604-9, 236-086-3, 238-009-9 | 85-42-7, 13149-00-3, 14166-21-3 | 2012/12/19 | Equivalent level of concern having probable serious effects to human health (Article 57 f) | ED/169/2012 |
| 119 | Pyrochlore, antimony lead yellow | 232-382-1 | 8012-00-8 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 120 | Henicosafluoroundecanoic acid | 218-165-4 | 2058-94-8 | 2012/12/19 | vPvB (Article 57 e) | ED/169/2012 |
| 121 | 4-Aminoazobenzene | 200-453-6 | 60-09-3 | 2012/12/19 | Carcinogenic (Article 57a) | ED/169/2012 |
| 122 | Silicic acid, lead salt | 234-363-3 | 11120-22-2 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 123 | Lead titanium zirconium oxide | 235-727-4 | 12626-81-2 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 124 | Lead monoxide (lead oxide) | 215-267-0 | 1317-36-8 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 125 | o-Toluidine | 202-429-0 | 95-53-4 | 2012/12/19 | Carcinogenic (Article 57a) | ED/169/2012 |
| 126 | 3-ethyl-2-methyl-2-(3-methylbutyl)-1,3-oxazolidine | 421-150-7 | 143860-04-2 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 127 | Dibutyltin dichloride (DBTC) | 211-670-0 | 683-18-1 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 128 | Lead bis(tetrafluoroborate) | 237-486-0 | 13814-96-5 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 129 | Lead dinitrate | 233-245-9 | 10099-74-8 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 130 | Silicic acid (H2Si2O5), barium salt (1:1), lead-doped [with lead (Pb) content above the applicable generic concentration limit for ’toxicity for reproduction’ Repr. 1A (CLP) or category 1 (DSD); the substance is a member of the group entry of lead compounds, with index number 082-001-00-6 in Regulation (EC) No 1272/2008] | 272-271-5 | 68784-75-8 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 131 | Trilead bis(carbonate)dihydroxide | 215-290-6 | 1319-46-6 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 132 | 4,4'-methylenedi-o-toluidine | 212-658-8 | 838-88-0 | 2012/12/19 | Carcinogenic (Article 57a) | ED/169/2012 |
| 133 | Diethyl sulphate | 200-589-6 | 64-67-5 | 2012/12/19 | Carcinogenic (Article 57a); Mutagenic (Article 57b) | ED/169/2012 |
| 134 | Dimethyl sulphate | 201-058-1 | 77-78-1 | 2012/12/19 | Carcinogenic (Article 57a) | ED/169/2012 |
| 135 | N,N-dimethylformamide | 200-679-5 | 68-12-2 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 136 | 4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated [covering well-defined substances and UVCB substances, polymers and homologues] | - | - | 2012/12/19 | Equivalent level of concern having probable serious effects to the environment (Article 57 f) | ED/169/2012 |
| 137 | 4-Nonylphenol, branched and linear [substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof] | - | - | 2012/12/19 | Equivalent level of concern having probable serious effects to the environment (Article 57 f) | ED/169/2012 |
| 138 | Furan | 203-727-3 | 110-00-9 | 2012/12/19 | Carcinogenic (Article 57a) | ED/169/2012 |
| 139 | Lead oxide sulfate | 234-853-7 | 12036-76-9 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 140 | Lead titanium trioxide | 235-038-9 | 12060-00-3 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 141 | Bis(pentabromophenyl) ether (decabromodiphenyl ether; DecaBDE) | 214-604-9 | 1163-19-5 | 2012/12/19 | PBT (Article 57 d); vPvB (Article 57 e) | ED/169/2012 |
| 142 | Dinoseb (6-sec-butyl-2,4-dinitrophenol) | 201-861-7 | 88-85-7 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 143 | 1,2-Diethoxyethane | 211-076-1 | 629-14-1 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 144 | N-methylacetamide | 201-182-6 | 79-16-3 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 145 | Tetralead trioxide sulphate | 235-380-9 | 12202-17-4 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 146 | Acetic acid, lead salt, basic | 257-175-3 | 51404-69-4 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 147 | [Phthalato(2-)]dioxotrilead | 273-688-5 | 69011-06-9 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 148 | Tetraethyllead | 201-075-4 | 78-00-2 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 149 | N-pentyl-isopentylphthalate | - | 776297-69-9 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 150 | Pentalead tetraoxide sulphate | 235-067-7 | 12065-90-6 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 151 | Heptacosafluorotetradecanoic acid | 206-803-4 | 376-06-7 | 2012/12/19 | vPvB (Article 57 e) | ED/169/2012 |
| 152 | Tricosafluorododecanoic acid | 206-203-2 | 307-55-1 | 2012/12/19 | vPvB (Article 57 e) | ED/169/2012 |
| 153 | 1-bromopropane (n-propyl bromide) | 203-445-0 | 106-94-5 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 154 | Dioxobis(stearato)trilead | 235-702-8 | 12578-12-0 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 155 | Pentacosafluorotridecanoic acid | 276-745-2 | 72629-94-8 | 2012/12/19 | vPvB (Article 57 e) | ED/169/2012 |
| 156 | Methoxyacetic acid | 210-894-6 | 625-45-6 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 157 | Methyloxirane (Propylene oxide) | 200-879-2 | 75-56-9 | 2012/12/19 | Carcinogenic (Article 57a); Mutagenic (Article 57b) | ED/169/2012 |
| 158 | Trilead dioxide phosphonate | 235-252-2 | 12141-20-7 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 159 | o-aminoazotoluene | 202-591-2 | 97-56-3 | 2012/12/19 | Carcinogenic (Article 57a) | ED/169/2012 |
| 160 | 4-methyl-m-phenylenediamine (toluene-2,4-diamine) | 202-453-1 | 95-80-7 | 2012/12/19 | Carcinogenic (Article 57a) | ED/169/2012 |
| 161 | Diisopentylphthalate | 210-088-4 | 605-50-5 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 162 | 1,2-Benzenedicarboxylic acid, dipentylester, branched and linear | 284-032-2 | 84777-06-0 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 163 | Biphenyl-4-ylamine | 202-177-1 | 92-67-1 | 2012/12/19 | Carcinogenic (Article 57a) | ED/169/2012 |
| 164 | Fatty acids, C16-18, lead salts | 292-966-7 | 91031-62-8 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 165 | Orange lead (lead tetroxide) | 215-235-6 | 1314-41-6 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 166 | 4,4'-oxydianiline and its salts | 202-977-0 | 101-80-4 | 2012/12/19 | Carcinogenic (Article 57a); Mutagenic (Article 57b) | ED/169/2012 |
| 167 | Diazene-1,2-dicarboxamide (C,C'-azodi(formamide)) | 204-650-8 | 123-77-3 | 2012/12/19 | Equivalent level of concern having probable serious effects to human health (Article 57 f) | ED/169/2012 |
| 168 | Sulfurous acid, lead salt, dibasic | 263-467-1 | 62229-08-7 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 169 | Lead cyanamidate | 244-073-9 | 20837-86-9 | 2012/12/19 | Toxic for reproduction (Article 57 c) | ED/169/2012 |
| 170 | α,α-Bis[4-(dimethylamino)phenyl]-4 (phenylamino)naphthalene-1-methanol (C.I. Solvent Blue 4) [with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)] | 229-851-8 | 6786-83-0 | 2012/6/18 | Carcinogenic (Article 57a) | ED/87/2012 |
| 171 | 1,3,5-tris[(2S and 2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione (β-TGIC) | 423-400-0 | 59653-74-6 | 2012/6/18 | Mutagenic (Article 57b) | ED/87/2012 |
| 172 | N,N,N',N'-tetramethyl-4,4'-methylenedianiline (Michler’s base) | 202-959-2 | 101-61-1 | 2012/6/18 | Carcinogenic (Article 57a) | ED/87/2012 |
| 173 | Diboron trioxide | 215-125-8 | 1303-86-2 | 2012/6/18 | Toxic for reproduction (Article 57 c) | ED/87/2012 |
| 174 | 1,2-bis(2-methoxyethoxy)ethane (TEGDME; triglyme) | 203-977-3 | 112-49-2 | 2012/6/18 | Toxic for reproduction (Article 57 c) | ED/87/2012 |
| 175 | Formamide | 200-842-0 | 75-12-7 | 2012/6/18 | Toxic for reproduction (Article 57 c) | ED/87/2012 |
| 176 | 4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol [with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)] | 209-218-2 | 561-41-1 | 2012/6/18 | Carcinogenic (Article 57a) | ED/87/2012 |
| 177 | Lead(II) bis(methanesulfonate) | 401-750-5 | 17570-76-2 | 2012/6/18 | Toxic for reproduction (Article 57 c) | ED/87/2012 |
| 178 | [4-[4,4'-bis(dimethylamino) benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium chloride (C.I. Basic Violet 3) [with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)] | 208-953-6 | 548-62-9 | 2012/6/18 | Carcinogenic (Article 57a) | ED/87/2012 |
| 179 | 1,2-dimethoxyethane; ethylene glycol dimethyl ether (EGDME) | 203-794-9 | 110-71-4 | 2012/6/18 | Toxic for reproduction (Article 57 c) | ED/87/2012 |
| 180 | [4-[[4-anilino-1-naphthyl][4-(dimethylamino)phenyl]methylene]cyclohexa-2,5-dien-1-ylidene] dimethylammonium chloride (C.I. Basic Blue 26) [with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)] | 219-943-6 | 2580-56-5 | 2012/6/18 | Carcinogenic (Article 57a) | ED/87/2012 |
| 181 | 1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC) | 219-514-3 | 2451-62-9 | 2012/6/18 | Mutagenic (Article 57b) | ED/87/2012 |
| 182 | 4,4'-bis(dimethylamino)benzophenone (Michler’s ketone) | 202-027-5 | 90-94-8 | 2012/6/18 | Carcinogenic (Article 57a) | ED/87/2012 |
| 183 | Phenolphthalein | 201-004-7 | 77-09-8 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 184 | N,N-dimethylacetamide | 204-826-4 | 127-19-5 | 2011/12/19 | Toxic for reproduction (article 57 c) | ED/77/2011 |
| 185 | 4-(1,1,3,3-tetramethylbutyl)phenol | 205-426-2 | 140-66-9 | 2011/12/19 | Equivalent level of concern having probable serious effects to the environment (article 57 f) | ED/77/2011 |
| 186 | Lead diazide, Lead azide | 236-542-1 | 13424-46-9 | 2011/12/19 | Toxic for reproduction (article 57 c), | ED/77/2011 |
| 187 | Lead dipicrate | 229-335-2 | 6477-64-1 | 2011/12/19 | Toxic for reproduction (article 57 c) | ED/77/2011 |
| 188 | 1,2-dichloroethane | 203-458-1 | 107-06-2 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 189 | Calcium arsenate | 231-904-5 | 7778-44-1 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 190 | Dichromium tris(chromate) | 246-356-2 | 24613-89-6 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 191 | 2-Methoxyaniline; o-Anisidine | 201-963-1 | 90-04-0 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 192 | Pentazinc chromate octahydroxide | 256-418-0 | 49663-84-5 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 193 | Zirconia Aluminosilicate Refractory Ceramic Fibres are fibres covered by index number 650-017-00-8 in Annex VI, part 3, table 3.1 of Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, and fulfil the three following conditions: a) oxides of aluminium, silicon and zirconium are the main components present (in the fibres) within variable concentration ranges b) fibres have a length weighted geometric mean diameter less two standard geometric errors of 6 or less micrometres (µm). c) alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content less or equal to 18% by weight | - | - | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011,ED/95/2012 |
| 194 | Arsenic acid | 231-901-9 | 7778-39-4 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 195 | Potassium hydroxyoctaoxodizincatedichromate | 234-329-8 | 11103-86-9 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 196 | Formaldehyde, oligomeric reaction products with aniline | 500-036-1 | 25214-70-4 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 197 | Lead styphnate | 239-290-0 | 15245-44-0 | 2011/12/19 | Toxic for reproduction (article 57 c) | ED/77/2011 |
| 198 | Bis(2-methoxyethyl) phthalate | 204-212-6 | 117-82-8 | 2011/12/19 | Toxic for reproduction (article 57 c) | ED/77/2011 |
| 199 | Trilead diarsenate | 222-979-5 | 3687-31-8 | 2011/12/19 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/77/2011 |
| 200 | Aluminosilicate Refractory Ceramic Fibres are fibres covered by index number 650-017-00-8 in Annex VI, part 3, table 3.1 of Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, and fulfil the three following conditions: a) oxides of aluminium and silicon are the main components present (in the fibres) within variable concentration ranges b) fibres have a length weighted geometric mean diameter less two standard geometric errors of 6 or less micrometres (µm) c) alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content less or equal to 18% by weight | - | - | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011,ED/95/2012 |
| 201 | Bis(2-methoxyethyl) ether | 203-924-4 | 111-96-6 | 2011/12/19 | Toxic for reproduction (article 57 c) | ED/77/2011 |
| 202 | 2,2'-dichloro-4,4'-methylenedianiline | 202-918-9 | 101-14-4 | 2011/12/19 | Carcinogenic (article 57 a) | ED/77/2011 |
| 203 | Cobalt dichloride | 231-589-4 | 7646-79-9 | 2011/06/20 - 2008/10/28 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/31/2011 / ED/67/2008 |
| 204 | 1,2-Benzenedicarboxylic acid, di-C6-8-branched alkyl esters, C7-rich | 276-158-1 | 71888-89-6 | 2011/6/20 | Toxic for reproduction (article 57c) | ED/31/2011 |
| 205 | Strontium chromate | 232-142-6 | 7789-06-2 | 2011/6/20 | Carcinogenic (article 57a) | ED/31/2011 |
| 206 | 1,2-Benzenedicarboxylic acid, di-C7-11-branched and linear alkyl esters | 271-084-6 | 68515-42-4 | 2011/6/20 | Toxic for reproduction (article 57c) | ED/31/2011 |
| 207 | 1-Methyl-2-pyrrolidone | 212-828-1 | 872-50-4 | 2011/6/20 | Toxic for reproduction (article 57c) | ED/31/2011 |
| 208 | 1,2,3-Trichloropropane | 202-486-1 | 96-18-4 | 2011/6/20 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/31/2011 |
| 209 | 2-Ethoxyethyl acetate | 203-839-2 | 111-15-9 | 2011/6/20 | Toxic for reproduction (article 57c) | ED/31/2011 |
| 210 | Hydrazine | 206-114-9 | 302-01-2, 7803-57-8 | 2011/6/20 | Carcinogenic (article 57a) | ED/31/2011 |
| 211 | Cobalt(II) diacetate | 200-755-8 | 71-48-7 | 2010/12/15 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/95/2010 |
| 212 | 2-Ethoxyethanol | 203-804-1 | 110-80-5 | 2010/12/15 | Toxic for reproduction (article 57c) | ED/95/2010 |
| 213 | Cobalt(II) sulphate | 233-334-2 | 10124-43-3 | 2010/12/15 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/95/2010 |
| 214 | Acids generated from chromium trioxide and their oligomers. Names of the acids and their oligomers: Chromic acid, Dichromic acid, Oligomers of chromic acid and dichromic acid. | 231-801-5, 236-881-5 | 7738-94-5, 13530-68-2 | 2010/12/15 | Carcinogenic (article 57a) | ED/95/2010 |
| 215 | 2-Methoxyethanol | 203-713-7 | 109-86-4 | 2010/12/15 | Toxic for reproduction (article 57c) | ED/95/2010 |
| 216 | Chromium trioxide | 215-607-8 | 1333-82-0 | 2010/12/15 | Carcinogenic and mutagenic (articles 57 a and 57 b) | ED/95/2010 |
| 217 | Cobalt(II) carbonate | 208-169-4 | 513-79-1 | 2010/12/15 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/95/2010 |
| 218 | Cobalt(II) dinitrate | 233-402-1 | 10141-05-6 | 2010/12/15 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/95/2010 |
| 219 | Trichloroethylene | 201-167-4 | 79-01-6 | 2010/6/18 | Carcinogenic (article 57 a) | ED/30/2010 |
| 220 | Potassium dichromate | 231-906-6 | 7778-50-9 | 2010/6/18 | Carcinogenic, mutagenic and toxic for reproduction (articles 57 a, 57 b and 57 c) | ED/30/2010 |
| 221 | Tetraboron disodium heptaoxide, hydrate | 235-541-3 | 12267-73-1 | 2010/6/18 | Toxic for reproduction (article 57 c) | ED/30/2010 |
| 222 | Boric acid | 233-139-2, 234-343-4 | 10043-35-3, 11113-50-1 | 2010/6/18 | Toxic for reproduction (article 57 c) | ED/30/2010 |
| 223 | Ammonium dichromate | 232-143-1 | 7789-09-5 | 2010/6/18 | Carcinogenic, mutagenic and toxic for reproduction (articles 57 a, 57 b and 57 c) | ED/30/2010 |
| 224 | Sodium chromate | 231-889-5 | 7775-11-3 | 2010/6/18 | Carcinogenic, mutagenic and toxic for reproduction (articles 57 a, 57 b and 57 c) | ED/30/2010 |
| 225 | Disodium tetraborate, anhydrous | 215-540-4 | 1303-96-4, 1330-43-4, 12179-04-3 | 2010/6/18 | Toxic for reproduction (article 57 c) | ED/30/2010 |
| 226 | Potassium chromate | 232-140-5 | 7789-00-6 | 2010/6/18 | Carcinogenic and mutagenic (articles 57 a and 57 b). | ED/30/2010 |
| 227 | Acrylamide | 201-173-7 | 79-06-1 | 2010/3/30 | Carcinogenic and mutagenic (articles 57 a and 57 b) | ED/68/2009 |
| 228 | Lead sulfochromate yellow (C.I. Pigment Yellow 34) | 215-693-7 | 1344-37-2 | 2010/1/13 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c)) | ED/68/2009 |
| 229 | Lead chromate molybdate sulphate red (C.I. Pigment Red 104) | 235-759-9 | 12656-85-8 | 2010/1/13 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/68/2009 |
| 230 | 2,4-Dinitrotoluene | 204-450-0 | 121-14-2 | 2010/1/13 | Carcinogenic (article 57a) | ED/68/2009 |
| 231 | Anthracene oil | 292-602-7 | 90640-80-5 | 2010/1/13 | Carcinogenic1, PBT and vPvB (articles 57a, 57d and 57e) | ED/68/2009 |
| 232 | Anthracene oil, anthracene paste, anthracene fraction | 295-275-9 | 91995-15-2 | 2010/1/13 | Carcinogenic2, mutagenic3, PBT and vPvB (articles 57a, 57b, 57d and 57e) | ED/68/2009 |
| 233 | Anthracene oil, anthracene-low | 292-604-8 | 90640-82-7 | 2010/1/13 | Carcinogenic2, mutagenic3, PBT and vPvB (articles 57a, 57b, 57d and 57e) | ED/68/2009 |
| 234 | Diisobutyl phthalate (DIBP) | 201-553-2 | 84-69-5 | 2010/1/13 | Toxic for reproduction (article 57c) Endocrine disrupting properties (Article 57(f) - human health) |
ED/68/2009 C(2017)4462 ED/30/2017 |
| 235 | Tris(2-chloroethyl)phosphate | 204-118-5 | 115-96-8 | 2010/1/13 | Toxic for reproduction (article 57c) | ED/68/2009 |
| 236 | Lead chromate | 231-846-0 | 7758-97-6 | 2010/1/13 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/68/2009 |
| 237 | Anthracene oil, anthracene paste | 292-603-2 | 90640-81-6 | 2010/1/13 | Carcinogenic2, mutagenic3, PBT and vPvB (articles 57a, 57b, 57d and 57e) | ED/68/2009 |
| 238 | Pitch, coal tar, high temp. | 266-028-2 | 65996-93-2 | 2010/1/13 | Carcinogenic, PBT and vPvB (articles 57a, 57d and 57e) | ED/68/2009 |
| 239 | Anthracene oil, anthracene paste,distn. lights | 295-278-5 | 91995-17-4 | 2010/1/13 | Carcinogenic2, mutagenic3, PBT and vPvB (articles 57a, 57b, 57d and 57e) | ED/68/2009 |
| 240 | Lead hydrogen arsenate | 232-064-2 | 7784-40-9 | 2008/10/28 | Carcinogenic and toxic for reproduction (articles 57 a and 57 c) | ED/67/2008 |
| 241 | Benzyl butyl phthalate (BBP) | 201-622-7 | 85-68-7 | 2008/10/28 | Toxic for reproduction (article 57c) Endocrine disrupting properties (Article 57(f) - human health) |
ED/67/2008 C(2017)4462 ED/30/2017 |
| 242 | Bis(2-ethylhexyl) phthalate (DEHP) | 204-211-0 | 117-81-7 | 2014/12/17; 2008/10/28 | Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - environment) Endocrine disrupting properties (Article 57(f) - human health) |
ED/67/2008 ED/108/2014 C(2017)4462 ED/30/2017 |
| 243 | Bis(tributyltin)oxide (TBTO) | 200-268-0 | 56-35-9 | 2008/10/28 | PBT (article 57d) | ED/67/2008 |
| 244 | 5-tert-butyl-2,4,6-trinitro-m-xylene (musk xylene) | 201-329-4 | 81-15-2 | 2008/10/28 | vPvB (article 57e) | ED/67/2008 |
| 245 | Diarsenic trioxide | 215-481-4 | 1327-53-3 | 2008/10/28 | Carcinogenic (article 57a) | ED/67/2008 |
| 246 | Triethyl arsenate | 427-700-2 | 15606-95-8 | 2008/10/28 | Carcinogenic (article 57a) | ED/67/2008 |
| 247 | Diarsenic pentaoxide | 215-116-9 | 1303-28-2 | 2008/10/28 | Carcinogenic (article 57a) | ED/67/2008 |
| 248 | Sodium dichromate | 234-190-3 | 7789-12-0, 10588-01-9 | 2008/10/28 | Carcinogenic, mutagenic and toxic for reproduction (articles 57a, 57b and 57c) | ED/67/2008 |
| 249 | Dibutyl phthalate (DBP) | 201-557-4 | 84-74-2 | 2008/10/28 | Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - environment) Endocrine disrupting properties (Article 57(f) - human health) |
EU/2017/4462 D(2023)8585-DC ED/30/2017 ED/67/2008 |
| 250 | 4,4'- Diaminodiphenylmethane (MDA) | 202-974-4 | 101-77-9 | 2008/10/28 | Carcinogenic (article 57a) | ED/67/2008 |
| 251 | Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins) | 287-476-5 | 85535-84-8 | 2008/10/28 | PBT and vPvB (articles 57 d and 57 e) | ED/67/2008 |
| 252 | Anthracene | 204-371-1 | 120-12-7 | 2008/10/28 | PBT (article 57d) | ED/67/2008 |
| 253 | Hexabromocyclododecane (HBCDD) and all major diastereoisomers identified: Alpha-hexabromocyclododecane Beta-hexabromocyclododecane Gamma-hexabromocyclododecane | 247-148-4 and 221-695-9 | 25637-99-4, 3194-55-6 (134237-50-6) (134237-51-7) (134237-52-8) | 2008/10/28 | PBT (article 57d) | ED/67/2008 |